THE THERAPEUTIC EFFECT OF BATROXOBIN(DF-521) ON OTITIS MEDIA WITH EFFUSION
- VernacularTitle:东菱克栓酶(Batroxobin,DF-521)对渗出性中耳炎的治疗作用
- Author:
Yihui ZOU
;
Deliang HUANG
;
Yaoyu FANG
- Publication Type:Journal Article
- Keywords:
Batroxobin;
otitis media with effusion;
adhesive otitis media
- From:
Medical Journal of Chinese People's Liberation Army
1983;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
To investigate the role of fibrinolysis in adhesion formation in the middle ear,40 patients(45 ears) with otitis media with exudation (OME) were randomly divided into 3 groups:Dexamethasone(G1),Batroxobin1BU/ml(G2),and Batroxobin 2BU/ml(G3).The results were assessed by tympanotomy and irigation to compare the efficacy of treatment of batroxobin and dexamethasone.31 patients (33 ears) were analyzed for statistical significance.The efficacy of the treatment was evaluated by qualitative analysis of symptom and the Hearing Threshold of Air conduction of pure tone audiometry (AHT) at frequencies 0 25～2kHz,and by quantitative analysis of AHT.Cure rates of G1,G2,G3 were 41 7%(5/12),54 5%(6/11),70%(7/10) respectively;G3 was higher than G1 and G2( P 0 05). After treatment AHT of G3 was lower than G2 and G1( P
