Pseudohypoparathyroidism (a report of 6 patients in a family)
- VernacularTitle:假性甲状旁腺机能减退症(附一家系六例报告)
- Author:
Rungen LI
;
Xinqiang JIAO
;
Zhilie CHEN
- Publication Type:Journal Article
- Keywords:
Pseudohypoparathyroidism;
Bone diseases, metabolic;
Diagnostic imaging
- From:
Chinese Journal of Radiology
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To improve the recognition and diagnosis of pseudohypoparathyroidism (PHP). Methods Six subjects with PHP of 4 generations in one family were investigated and studied. There were 4 males (including 2 deaths) and 2 females. The age of 4 surviving patients was from 8 to 55 years. All cases were proved by clinical biochemistry tests. Plain film of hands and head CT scans were performed in 2 selected patients. Results The somatotype of Albright hereditary osteodystrophy (AHO) and short fingers and toes were found in all cases. Radiologic features were as follows:(1)short metacarpals and phalanges.(2)skull thickening and symmetrical calcification of basal ganglia. Conclusion The diagnosis of PHP can be established by close combination of radiologic findings and clinical manifestations.
