Effect of nitric oxide (NO) on dependence and tolerance of normorphine (NM) in the guinea-pig ileum in vitro
- VernacularTitle:NO对去甲吗啡在离体豚鼠回肠上依赖性耐受性产生的作用
- Author:
Mingzheng ZHOU
;
Yanna LI
- Publication Type:Journal Article
- Keywords:
guinea pig ileum;
nitric oxide;
normorphine;
drug dependence;
drug tolerance
- From:
Chinese Pharmacological Bulletin
1987;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05. The ratio of NM (200 nmol? L-l) plus NOArg (0.1 mmol. L-1 ) is 0.47 ? 0.05, compared with control (n = 6, P 0 .05). CONCLUSIONS These results suggest that NO has important role on dependence and tolerance of NM in the guinea Pig ileum.