RESEARCH OF BONE REGENERATION WITH CULTURED OSTEOBLASTS SEEDED IN POROUS CORAL-HYDROXYLAPATITE
- VernacularTitle:成骨细胞接种于珊瑚-羟基磷灰石构建骨组织的研究
- Author:
Fan WU
;
Weidong YANG
;
Delin LEI
- Publication Type:Journal Article
- Keywords:
tissue engineering;
osteoblasts;
hydroxylapatite
- From:
Medical Journal of Chinese People's Liberation Army
1981;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Rabbit osteoblasts were isolated, expanded in vitro, and then seeded into coral-hydroxylapatite. The osteoblasts/coral-hydroxylapatite composite was were implanted into the muscles of rabbits′ back. Bone regeneration was observed 4, 8 weeks after implantation by histological and scanning electron microscopic examinations.The results showed that osteoblasts could adhere and proliferate well on the surface of coral-hydroxylapatite. 4 weeks after implantation osteoid tissue was observed, 8 weeks after implantation large amount of new bone was found. It suggested that osteoblasts/coral-hydroxylapatite composite may be used for bone tissue engineering.
