DETECTION OF HUMAN PAPILLOMAVIRUS DNA OF ORAL SQUAMOUS CELL CARCINOMAS BY IN SITU HYBRIDIZATION
- VernacularTitle:口腔鳞癌组织中人乳头瘤病毒DNA的原位杂交研究
- Author:
Jingqiu BU
;
Min HU
;
Yali LU
- Publication Type:Journal Article
- Keywords:
mouth neoplasms;
in situ hybridization;
papillomavirus, human
- From:
Medical Journal of Chinese People's Liberation Army
1982;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
By using digoxin labelled human papillomavirus(HPV) 6/11 and HPV16/18 probes,and hybridization in situ technique, the HPV DNA sequence in 50 cases of oral SCC was detected. The results showed that among them ,16 cases(32%) were positive for HPV16/18 DNA, none of the cases of OSCC was positive for HPV6/11 DNA. It was suggested that HPV16/18 in oral SCC was confirmed to be closely related with the cause of OSCC.
