STUDY OF THE CORRELATION BETWEEN ANGIOGENESIS AND PROGNOSIS OF BREAST CARCINOMA
- VernacularTitle:乳腺癌血管生成与预后的相关性
- Author:
Fulin WANG
;
Lixin WEI
;
Lezhen CHEN
- Publication Type:Journal Article
- Keywords:
breast neoplasms;
prognosis;
neovascularization, pathologic
- From:
Medical Journal of Chinese People's Liberation Army
1982;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
92 specimens from patients with invasive ductal carcinoma were investigated. The expression of vascular endothelial growth factor (VEGF) was demonstrated by immunocytochemical staining with an antibody against VEGF and was quantitatively estimated by using computerized image analysis system. Vessels were immunohistochemically highlighted by using an antibody to CD34, and microvessel density (MVD) was quantified. The postoperative survey in univariate analysis showed that the relapse-free-survival (RFS) time of patients with more than 87 microvessels in single microscopic field was significantly worse compared to that of patients with less than 87 microvessels in node-negative patients (P
