HEAT SHOCK PROTEINS ARE INVOLVED IN CARDIOPROTECTION OF PERCUTANEOUS TRANSLUMINAL MYOCARDIAL LASER REVASCULARIZATION
- VernacularTitle:激光心肌血管重建术诱导热休克蛋白表达上调
- Author:
Xiuhua LIU
;
Xudong WU
;
Shiwe WANG
- Publication Type:Journal Article
- Keywords:
transmyocardial laser revascularization;
heat shock proteins;
myocardial infarct;
pig
- From:
Medical Journal of Chinese People's Liberation Army
1982;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
To investigate the cardioprotective effect of percutaneous transluminal myocardial laser revascularization (PTMR) and its mechanism, in the ischemia/reperfusion (I/R) model of in vivo porcine heart, the effect of PTMR on myocardial infarct size (IS) was observed using TTC method,and expression of heat shock protein (HSP) 70 and 86 in myocardium was detected with Western blotting. It was found that PTMR significantly limited the myocardial IS induced by I/R (32%?3% vs 56%?7% in control group, P
