EXPRESSION OF VEGF AND bFGF IN TRANSITIONAL CELL CARCINOMA OF BLADDER AND ITS RELATIONSHIP WITH THE FORMATION OF MICROVESSELS
- VernacularTitle:膀胱癌中VEGF、bFGF表达及与微血管定量的关系
- Author:
Qixing SHI
;
Fang LI
;
Tongca LIU
- Publication Type:Journal Article
- Keywords:
bladder neoplasms;
endothelial growth factor;
fibroblast growth factor,basic
- From:
Medical Journal of Chinese People's Liberation Army
1982;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
To investigate the expression of vascular endothelial growth factor(VEGF) and basic fibroblast growth factor(bFGF) in primary transitional cell carcinoma(TCC) of bladder,and to determine their relationship with magnitude of angiogenesis.Both growth factor were assayed using immunohistochemical technique in 62 cases of TCC.The relationship between the expression of VEGF and bFGF in invasive neoplastic tissues and magnitude of angiogenesis were also investigated.The positive expression rates of VEGF and bFGF in neoplastin tissues were 56 5% and 46 8%,respectively.The expression of VEGF and bFGF showed positive relationship with tumor grades,stages,high recurrence, and shorter survival( P
