THE EXPRESSION OF APOPTOSIC GENES BCL-2,BAX AND FAS IN ENDOMETRIOSIS
- VernacularTitle:凋亡调节基因bcl-2,bax和fas在子宫内膜异位症中的表达
- Author:
Yunxia WANG
;
Yali LI
;
Jingxiang HUANG
- Publication Type:Journal Article
- Keywords:
Endometriosis Apoptosis Genes,bcl 2,bax,fas Apoptotic rate
- From:
Medical Journal of Chinese People's Liberation Army
1982;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
We examined eutopic,ectopic endometria and peritoneal fluid macrophages from 22 patients with endometriosis(EMS) and 14 women without EMS.To obtain evidence for the induction of programmed cell death,apoptotic cells were identified using a modified terminal deixynucleotidyltransferasebiotin nick end labeling method(TUNEL).To evaluate cell death repressor activity,bcl 2,bax and fas genes expression was examined using immunohistochemical staining. The results showed that bcl 2 expression in eutopic,ectopic endometrium and peritoneal fluid macrophages with EMS was significantly increased compared with no EMS( P
