THE DISTRIBUTION AND SIGNIFICANCE OF cag Ⅰ IN HELICOBACTER PYLORI ISOLATED FROM CHINESE PATIENTS
- VernacularTitle:cagⅠ在中国人群感染幽门螺杆菌中的分布及意义
- Author:
Jiong LIU
;
Guoming XU
;
Yanfan GONG
- Publication Type:Journal Article
- Keywords:
Helicobacter pylori;
cag pathogenicity island;
cag Ⅰ
- From:
Medical Journal of Chinese People's Liberation Army
1981;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
To investigate the distrbution of cag Ⅰin Helicobacter pylori(Hp) isolated from Chinese patients, and its relationship to gastroduodenal diseases. Fragment in cag Ⅰ was amplified by polymerase chain reaction(PCR) in 107 Hp strains from Chinese patients. Results The amplicom to cag Ⅰ was positive in 93 strains, of which 57 strains came from patients with chronic gastritis, 31 strains from peptic ulcer, and 5 strains from gastric carcinoma.Conclusion Existance of cag Ⅰ of Hp strains was popular in the Chinese population, but no data had proven the relation ship between the existence of cag 1and occurrence of Hp related diseases and inflammatory infiltration in gastric mucosa.
