QUANTITATIVE ANALYSIS OF E-CADHERIN AND ?-CATENIN IN TRANSITIONAL CELL CARCINOMA OF BLADDER
- VernacularTitle:膀胱移行细胞癌E-钙粘附蛋白和?连接素表达的定量研究
- Author:
Peng DU
;
Shaozeng ZHANG
;
Li MA
- Publication Type:Journal Article
- Keywords:
Bladder neoplasms;
Cadherins;
Flow cytomet
- From:
Medical Journal of Chinese People's Liberation Army
1981;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To measure the expression of E cadherin (E cad) and ? catenin (CTN) in transitional cell carcinomas (TCC) of bladder and to study the relationship between the expression and biological behavior of the carcinoma. Methods:Expression of E cad and ? CTN were measured by flow cytometry in 30 cases of frozen bladder carcinomas. Results: The fluorescence index (FI) of E cad and ? CTN of tumor cells were 0.5677?0.3194 and 0.5726?0.2895, respectively,which were significantly lower than those of normal bladder mucosa ( P
