Effect of radiotherapy on cellular kinetics of peripheral blood monocytes in patients with malignant tumors
- VernacularTitle:放射治疗对恶性肿瘤患者血细胞动力学的影响
- Author:
Zhenying ZHOU
;
Yueqing ZHU
;
Xiaoliu WU
- Publication Type:Journal Article
- Keywords:
Neoplasms/radiotherapy;
Hemocyte/radiation effects;
Cellular kinetics;
Flow cytometry
- From:
Chinese Journal of Radiation Oncology
1992;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of radiotherapy on cellular kinetics of peripheral blood monocytes in patients with malignant tumors. Methods In patients with malignant tumors, apoptosis and proliferative activity of peripheral blood monocytes were monitored and compared before, during and after radiotherapy. Results Apoptosis and S phase fraction in cancer patients on radiotherapy were higher as compared to these without radiotherapy or the normal control group (8.93%?6.94%, 0.20%?0.20%, 0.15% ?0.13%, and 1.23%?1.15%, 0.54%?0.46%, and 0.33%?0.26%,respectively,F=5.77, P