Uterine artery embolization with Pingyangmycin lipiodol emulsion for treatment of symptomatic uterine fibroids
- VernacularTitle:平阳霉素碘油乳剂子宫动脉栓塞治疗症状性子宫肌瘤
- Author:
Yanhao LI
;
Biao LIU
;
Qingle ZENG
- Publication Type:Journal Article
- Keywords:
Uterine neoplasms;
Embolization,therapeutic;
Iodized oil;
Antibiotics,antineoplastic
- From:
Chinese Journal of Radiology
2000;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effectiveness and side effects of uterine arterial embolization with Pingyangmycin(a homogenous bleomycin) lipiodol emulsion(PLE) for symptomatic uterine fibroids. Methods Uterine arterial embolization with PLE was performed in 25 patients.The improvement of symptoms and uterine size changes were followed up in 3-18 months(mean 6 months) after the procedure. Results All but 2 cases were successfully treated bilaterally.Superselective angiography showed enlargement of uterine artery,accompanied by tortuous branches.The uterine size was increased.The uterus itself was significantly stained and emptied slowly. Coagulation necrosis was found in resected fibroids after embolization in 3 patients. One month after the procedure, a mean 40% reduction of uterine volume was obtained in 18 followed up cases.The clinical symptoms were relieved significantly. The main side effects were hypogastic pain(13/25),which was intense in 6 cases. Conclusion Uterine arterial embolization with PLE is a good non surgical therapy in symptomatic uterine fibroids with mild side effects.
