The measurement study of MR imaging in vascular dementia
- VernacularTitle:血管性痴呆的MRI定量研究
- Author:
Liang WANG
;
Kuncheng LI
- Publication Type:Journal Article
- Keywords:
Dementia,vascular;
Magnetic resonance imaging;
Cerebral infarction
- From:
Chinese Journal of Radiology
2000;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To identify the neuroimaging determinants which could predict the occurrence of the vascular dementia (VaD). Methods The findings of cranial MRI were compared in 30 VaD patients and 30 stroke without dementia (SWD) patients by means of quantitative measurement of some indexes. The indexes of measurement included the cerebral white matter lesion (WML) area, the cerebral infarct area, the ratio of ventricle to brain(VBR) and the ratio between the areas of the corpus callosum and supratentorial brain at the midsaggittal plane. Discriminant analysis was used to search for the indexes which could contribute significantly to distinguishing the two groups. Results Small cerebral vessel disease and multi infarct were two major basal diseases of VaD in this series. The WML areas( t =-3.544, P =0.000), the left cortical infarct( Z =-2.538, P =0.011) and VBR ( t =4.475, P =0.000) were significantly higher and the corpus collsum areas( t = -4 616, P =0.000) was significantly lower in the VaD group than that in the SWD group. The indexes that could significantly discriminate the two groups was: callosal atrophy, ventricle to brain ratio, WML area, left cortical infarct area, left parietal infarct area, total cortical infarct area. Conclusions Callosal atrophy, lateral ventricle enlargement and extensive WML are important predictors of incidence of dementia in the small vessel disease; however, left cortical infarct, especially left parietal infarct, is important predictor of incidence of dementia in the multi infarct.
