THE CHRONOLOGICAL CHANGES IN GASTRIC MUCOSAL HYDROPHOBICITY AND THE CONTENT OF SURFACE ACTIVE PHOSPHOLIPID IN RATS UNDER WATER IMMERSION STRESS CONDITIONS
- VernacularTitle:应激状态下大鼠胃粘膜疏水性及表面活性磷脂的变化
- Author:
Xianbao ZHAN
;
Zhaoshen LI
;
Yimi DUAN
- Publication Type:Journal Article
- Keywords:
stress;
peptic ulcer;
gastric mucosa;
phospholipids
- From:
Medical Journal of Chinese People's Liberation Army
1981;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
The aim of the study was to analyze the impact of stress on gastric mucosal hydrophobicity and the dontent of phospholipid in gastric glandular adherent mucus gel layer in rat. Forty rats were randomly divided into four groups, which were control group, 0.5, 1 and 2 h after water immersion restraint stress groups. The gastric mucosal contact angle and the content of phospholipid in mucosal surface scraping material (SSM) of glandualar stomach and gastric mucosal ulcer index were measured. The gastric mucosal contact angle in each group was (38.0?2.4)?、(26 8?1 8)?、(20 0?1 4)? and (14 4?3 3)? respectively. The content of phospholipid in SSM per gram of glandular stomach in each group were (46 76?4 73)、(32 49?9 45)、(25 51?5 78)、(18 14?7 91)、(36 76?4 73)?g respectively and the ulcer index was 0、2.8?1.0、6.0?1.6 and 11.4?3.1 respectively. The three parameters showed significant changes in stress conditions as compared with those in normal control ( P
