EFFECT OF OMEPRAZOLE ON THE INTRAGASTRIC pH AND THE PREVENTION OF UPPER GASTRONINTESTINAL BLEEDING IN PATIENTS RECEIVING BRAIN SURGERY
- VernacularTitle:奥美拉唑对颅脑手术病人胃内pH的影响及对上消化道出血预防的临床研究
- Author:
Yinxue LEI
;
Zhaoshen LI
;
Xianba ZHAN
- Publication Type:Journal Article
- Keywords:
neurosurgery;
stress ulcer;
omeprazole;
gastric acid
- From:
Medical Journal of Chinese People's Liberation Army
1981;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
The aim of the study was to investigate the effect of Omeprazole on the intragastric pH and the prevention of upper gastrointestinal bleeding in patients undergoing brain surgery. Twenty patients who received brain surgery were randomly divided into two groups. 72 hour intragastric pH monitoring was carried out in all these patients beginning 4 hours before the operation. After the operation, 10 patients in the control group received therapy, the other 10 patients in Omeprazole group received Omeprazole 40 mg intravenously once daily in addition to routine therapy. In brain surgery patients, the intragastric pH increased during the operation ( P
