THE EFFECT OF RADIX SALVIAE MILTORRHIZAE (RSM) ON LIPOPEROXIDATION OF LDL AND ISCHEMIC BRAIN INJURY IN CHOLESTEROL FED RABBITS
- VernacularTitle:丹参抗LDL的脂质过氧化和脑缺血损伤的研究
- Author:
Rongxin ZHANG
;
Weiping WU
;
Xiaosh ZHANG
- Publication Type:Journal Article
- Keywords:
cholesterol, dietary;
lipoproteins, LDL;
lipid peroxide;
cerebral ischemia;
salviae miltorrhizae
- From:
Medical Journal of Chinese People's Liberation Army
1981;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
The blood lipids and lipid peroxide (LPO) were analysed in rabbits fed with 1% cholesterol in feeding ( n =19) and with standard feeding ( n =15) after 5 weeks of feeding.The plasma LDL was isolated and ox LDL was obtained by thin layer chromatography (TLC).Cerebral ischemia was induced by ligation of left common carotid artery.The antioxidation and antiischemia injury property of RSM was also observed with TLC and electron microscopy.The results showed that the plasma LPO,FFA,CH and PL levels in 1% cholesterol fed rabbits were much higher than those of rabbits with standard feeding( P
