Progress in study of potassium channels in human cardiomyocytes
- VernacularTitle:人心肌细胞钾道通研究进展
- Author:
Yong LIANG
;
Xiaoliang WANG
- Publication Type:Journal Article
- Keywords:
human cardiomyocytes;
potassium channels;
molecular biology;
electrophysiology;
pharmacology
- From:
Chinese Pharmacological Bulletin
1998;0(S1):-
- CountryChina
- Language:Chinese
-
Abstract:
Potassium channels which are targets of antiarrhythmic drugs (class III) play an important role in cardiomyocyte membrane. Recently, with the application of molecular biology techniques , development of cloned potassium channels, successful isolation of human cardiomyocytes and research of single channel, scientists have learnedmore characteristics of kinetics, electrophysiology and pharmacology of potassium channels. All these help them to develop and study new antiarrhythmic drugs.