The progress on study of S_(100) proteins
- VernacularTitle:神经系统S_(100)蛋白研究进展
- Author:
Kai WANG
;
Yuan WANG
;
Chuangen MA
- Publication Type:Journal Article
- Keywords:
S100 protein;
neuron;
glia;
neu- rotrophic factor PKC;
[Ca2+]1;
LTP
- From:
Chinese Pharmacological Bulletin
1998;0(S1):-
- CountryChina
- Language:Chinese
-
Abstract:
S100 proteins are a group of Ca2+ binding proteins. The main type of S100 proteins in nervous system (NS) is S1000B produced by astroglia cells and Schwann's cells. Recently, there are many researchs in the world which focuses on S100B biological activity and its mechanism, and these studies suggest that S100B plays a significant role inneuron development, neurite outgrowth and synaptic plasticity. We make a brief review in the field of S1000B biological property, distribution, biological activity and mechanism in NS. KEY WORDS S100 protein; neuron; glia; neu-rotrophic factor PKC; [Ca2+],;LTP
