Recent progress on the treatment of BPH with ?-adrenoceptor antogonists
- VernacularTitle:?受体阻断剂治疗BPH研究进展
- Author:
Zhihui YANG
;
Leiming REN
;
Xiaoping YANG
;
Shaoxuan FU
;
Yunshan LI
- Publication Type:Journal Article
- Keywords:
BPH ( benign prostatic hyperplasia);
medicine treatment;
a adrenoceptor antogomsts;
uroselectivity
- From:
Chinese Pharmacological Bulletin
1998;0(S1):-
- CountryChina
- Language:Chinese
-
Abstract:
a adrenoceptor-mediated increases in smooth muscle tone of the prostate gland and urethra acts as a dynamic factor for BPH-related obstruction of the urethra, a1 adrenoceptor antagonists are considered as the first-line therapy for the patients with BPH. The search for selective a1A a-drenoceptor antogonists with high uroselectivity is strategical for drug discovery research.
