Clinical applications of misoprostol
- VernacularTitle:米索前列醇的临床应用
- Author:
Weihong ZHENG
;
Naigong WANG
;
Juntian ZHANG
- Publication Type:Journal Article
- Keywords:
misoprostol;
peptic ulcer;
terminated early pregnancy;
anti-allergic disorders
- From:
Chinese Pharmacological Bulletin
1998;0(S1):-
- CountryChina
- Language:Chinese
-
Abstract:
Misoprostol, a prostaglandin E1 analogue, have variety clinical applications. In early 80's, misoprostol is currently licensed primarily to prevent non-steroidal anti-inflammatory drug-associated gastric and duodenal ulcers. Further work shows the drugs have protection to hepatic and renal and prevention of inflammatory and allergic disorders. When combined with mifepristone,complete abortion rate is 95%. On the other hand, misoprostol is also an effective agent for cervical ripening and labor induction. It have no serious side effect, as a result, misoprostol is a drug of high effect and low toxicity, deserving popularization, but man and pregnant woman must prudent.
