The relationship between antiendothelial cell antibodies and anticardiolipin antibodies
- VernacularTitle:狼疮性肾炎中抗内皮细胞抗体和抗心磷脂抗体的关系
- Author:
Hui GENG
;
Youkang ZHANG
;
Minghui ZHAO
- Publication Type:Journal Article
- Keywords:
Antiendothlial cell antibodies Anticardiolipin antibodies Lupus nephritis
- From:
Chinese Journal of Nephrology
1997;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between antiendothelial cell antibodies(AECA)and anticardiolipin antibodies(ACA)in patients with lupus nephritis. Methods 58 sera from patients with lupus nephritis were studied. ELISA technique were used to detect both AECA and ACA, and immunoblotting was performed to determine specific endothelial targets. Results The prevalence of IgG-AECA and IgG-ACA positive were 36.2% and 39.7% respectively in the patients with lupus nephritis. 17 out of 23 patients with ACA had higher titers of AECA, while only 4 out of 35 patients without ACA were AECA positive(P
