Exploring derivation of renocortical prostaglandins in C-BSA nephritis in rats
- VernacularTitle:大鼠阳离子化牛血清白蛋白肾炎肾脏前列腺素来源的探讨
- Author:
Zhijian LI
;
Youji LI
;
Qingyu KONG
- Publication Type:Journal Article
- Keywords:
C-BSA nephritis Platelet Prostaglandin
- From:
Chinese Journal of Nephrology
1997;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore derivation of renocortieal prostaglandins in C-BSA nephritis. Methods The interfering effect of goat-antiplatelet IgG serum(APS)on this model was studied. Results The levels of renocortical PGE_2、6-keto-PGF_(1?) (PGI_2)、TXA_2 were all reduced in experimental group. The pathological damage of experimental group were less severe in comparison with the model group. Proteinuria of the experimental group was alleviated. Conclusion Platelet may play a pathogenetic role of C-BSA nephritis and renocortical prostaglandins partly derive from platelets.
