The study of IL-1?,TNF-? and IL-6 gene expression and plasma levels on hemodialysis equipped with reused dialyzer
- VernacularTitle:透析器复用时IL-1?、TNF-?和IL-6基因表达及其血浆水平的研究
- Author:
Jiaqi QIAN
;
Zhiyuan YU
;
Hutti DAI
- Publication Type:Journal Article
- Keywords:
Gene expression IL-1? TNF-? IL-6 Dialyzer reuse
- From:
Chinese Journal of Nephrology
1997;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
RT-PCR and in situ hybridization were observed during dialyzer reuse. Results Every plasma cytokine level was decreased during reuse compared with first use dialyzer, but no significant difference was found between them. The levels of gene expression of IL-1?、TNF-? and IL-6 were different from the first use significantly. Conclusion If effective dialysis volumn was maintained, formaldehyde as disinfectant on reprocessing the dialyzer may amilorate membrane bio-compatibility. It would be benificial to decrease appearance of long term hemodialysis -related complications.