Hepatitis C virus markers in bemodialysis patients
- VernacularTitle:血液透析患者丙型肝炎病毒标志检测
- Author:
Yanjuan ZHU
;
Lutan LIAO
- Publication Type:Journal Article
- Keywords:
Hemodialysis Hepatitis C virus Nested PCR
- From:
Chinese Journal of Nephrology
1997;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
To investigate the hepatitis C virus (HCV) infection in hemodialysis patients. Methods Sixty patients were tested for anti-HCV IgG and anti-HCV IgM using a second generation enzyme-linked immunosorbent assay (ELISA); for HCV-RNA using a nested polymerase chain reaction (PCR) assay. Results Twenty seven patients were positive for anti-HCV IgG, 24 for anti-HCV IgM and 37 for HCV-RNA. The total positive rate of HCV markers was 63.3% in 60 hemodialysis patients. In transfused group, the positive rate of HCV markers was 69.9% , while in non-transfused was 42.9% . Conclusion The prevalence of HCV infection in hemodialysis patients is serious. Blood transfusion is the main way to transmit HCV. However, there may be other transmitting routes by the dialysis equipment.