Detection of Epstein-Barr virus in interstitial nephritis by in situ hybridization
- VernacularTitle:间质性肾炎中EB病毒的原位杂交检测
- Author:
Lihua BAO
;
Youkang ZHANG
;
Wanzhong ZOU
- Publication Type:Journal Article
- Keywords:
Interstitial nephritis Epstein-Barr virus In situ hybridization
- From:
Chinese Journal of Nephrology
1997;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
To investigate the location of Epstein-Barr virus (EBV) in renal tissues of patients with interstitial nephritis(IN). Methods By in situ hybridization. EBER1 was detected in renal tissues of 12 IN patients and 10 patients with minimal change nephropathy (MCN) as control group. Results EBER1 was found positive in 3 renal tissues of IN patients. It mainly distributed in the nuclei of renal tubular cells, infiltration cells and glomerular cells and 10 MCN patients were all negative. Conclusion EBV infection may play an important role in the pathogenesis of IN. In different types of IN, EBV infection may play different role.
