The influence of peritoneal dialysate on peritoneal macrophage releasing TNF-?
- VernacularTitle:腹膜透析液对腹腔巨噬细胞释放肿瘤坏死因子的影响
- Author:
Qiang YAO
;
Jiaqi QIAN
;
Yuhua JI
- Publication Type:Journal Article
- Keywords:
Dialysate Macrophage Tumor necrosis factor
- From:
Chinese Journal of Nephrology
1997;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
To investigate the damage on macrophage of the commercial peritoneal dialysis solution(CDS). Methods Macrophages were seperated from peritoneal fluid remained overnight of seven CAPD patients and TNF-a level of supernatant was determined and compared with those macrophages from uremic patients not yet recieving peritoneal dialysis. Results TNF-a levels of different glucose concentration decreased obviously in experimental group compared with control group, especially lower in 2.5% and 4.25% group. Conclusion In vivo experiment confirms that CDS possesses a long time inhibition on macrophage and this inhibition varies with different glucose concentrations.
