The biologic effect of cryopexy on retinal pigment epithelium barrier
- VernacularTitle:冷凝致视网膜色素上皮屏障改变的生物学效应
- Author:
Yimin XU
- Publication Type:Journal Article
- Keywords:
Retinal pigment epithelium;
Lanthanum;
Cryosurgery
- From:
Ophthalmology in China
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
With the tracer colloidal lanthanum,light micro- scope and transmission electron microscope in animal experiments,we studied the retinal pigment epithe- lium(RPE)barrier of 48 moderately severe cryoge- nic lesions on the retina of 21 rabbit eyes at dif- ferent intervals after cryopexy.Our findings showed that:1.the repair of disrupted RPE barrier by cryopexy was poor or incomplete,the regenerated RPE cells in restored RPE barrier of some cryogenic lesions showed degeneration and decompensation dur- ing the recovery period,and the tracer in choroidal capillaries leaked into the degenerated RPE cells and the subretinal space;2.the biologic effect of cryo- pexy on the retina was closely related to the acting time and the size of cryoapplication probe;and 3. the damaged grade of subretinal space caused by moderately severe cryopexy was comparable to Lincoff and Kreissig's criteria,but it was not absolute.
