The effect of Captopril on platelets cytosolic free calcium and platelets aggregation in renovascular hypertensive rats
- VernacularTitle:卡托普利对高血压大鼠血小板内游离钙和血小板功能的影响
- Author:
Xiangrong WEI
;
Hualin LI
;
Jinming LIN
;
Lian HU
- Publication Type:Journal Article
- Keywords:
hypertension;
platelets;
calci-um;
Captopril
- From:
Chinese Pharmacological Bulletin
1987;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
To evaluate effects and mechanism of Captopril on BP of 2 -kidney, 1 -clip reno-vascular hypertensive rats ( 2K1C - RHR ), Platelets cytosolic free calcium, concentration ([Ca2+]i) and platelets aggregation (PAg) are measured. The results are as follows: [Ca2+ ]; and PAg increase significantly (P
