Protective effect of gypenoside on brainstem ischemic injuries in dogs
- VernacularTitle:绞股蓝皂甙对犬脑干缺血性损伤的保护作用
- Author:
Qianning LI
;
Dongwu WANG
;
Jian ZHENG
- Publication Type:Journal Article
- Keywords:
brainstem ischemia;
gypenoside;
brainstem auditory evoked poten-tials;
phospholipase A2;
superoxide dismutase
- From:
Chinese Pharmacological Bulletin
1987;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
The brainstem ischemic injuries were produced by the occlusion of the basilar artery for 6 h in dogs. Gypenoside (150 mg ?kg-1)were intradudinally given at 3 h before the occlusion. We discovered that gypenoside alleviated the ischemic neuronal damage (histopathologically evaluated by the light and electronic microscope), ameliorated the abnormal changes of brainstem auditory evoked potentials (BAEP) (F
