Effects of selenium-enriched yeast on DTH in immunosuppressive mice
- VernacularTitle:富硒酵母对免疫功能低下小鼠DTH的影响
- Author:
Yuxian SHEN
;
Wei WEI
;
Anpin ZHANG
- Publication Type:Journal Article
- Keywords:
selenium-enriched yeast;
de-layed-type hypersensitivity (DTH);
spleen;
lymphocyte;
proliferation
- From:
Chinese Pharmacological Bulletin
1987;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
The effects of selenium-enriched yeast (Sey) on DTH in immunosuppressive mice have been investigated. It was found that Sey (30, 60, 90 mg?kg-l?d-1?6 d, ig) was able to antagonize lowered DTH by cyclophospha-mide (Cy); Meanwhile, the thymus and spleen weights were increased by Sey (30, or 60 mg?kg-1?d-1) in immunosuppressive mice. Sey also potentiated the lowered ConA and LPS-indu-ced proliferation of splenocytes in DTH mice at the doses of 30, 60, or 90 mg ?kg-1 and 60 or 90 mg?kg-1 respectively. These results suggested that Sey could enhance the functions of lymphocytes.
