Protective effect of anisodaminum on light-induced rat retinopathy/
- VernacularTitle:山莨菪碱对大鼠光性视网膜损伤的保护作用
- Author:
Ye LIANG
- Publication Type:Journal Article
- Keywords:
Retina/injury;
Radiation injury/prevention and control;
Atropine/analogy and derivatives;
Radiation-protective agents/pharmacology
- From:
Ophthalmology in China
1993;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Acute intermittent visible fluorescent light was used as an experimental light source (18175?300lux, 1 hour dark: 1 hour light, 3 cycles). After light exposure, the myeloperoxidase activity (MDA) levels increased in rat retina, and the retinal structure and blood-retinal barrier were damaged. When 2 doses of anisodaminum (10 mg/Kg) were given 12 hours and just before light exposure, MDA levels lowered and the retinal structure was protected.
