The effects of DNA ploidy measurement on pathologic diagnosis of limbus epithelial neoplasms
- VernacularTitle:角结膜缘上皮性肿瘤DNA含量测定对于病理诊断的意义
- Author:
Bin LI
- Publication Type:Journal Article
- Keywords:
Limbus neoplasm/quantitative pathology;
Photometric analysis/DNA ploidy measurement
- From:
Ophthalmology in China
1993;0(01):-
- CountryChina
- Language:Chinese
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Abstract:
An apparatus of true color medical photometric analysis, a quantitative pathologic technique, was adopted to measure DNA ploidy content in 51 cases with limbus epithelial neoplasm. According to the DNA pattern, the cells in the neoplasm were divided into 4 types: diploid (2C), tri-to tetraploid (3-4C), pentaploid (5C) and≥5C. In the lesion of epithelial hyperplasia, 2C-4C ceils accounted for 88.59%, and≥5C cells, 11.41%. In atypical hyperplasia, 2C-4C cells accounted for 58.62% and ≥5C cells, 41.38%. In the cases of carcinoma in situ and squamous cell carcinoma, 2C-4C cells accounted for 21.11% and 21.69%, and ≥5C cells, 78.89% and 78.31% respectively. These data were analyzed between each two groups by x~2 test (P
