LONG-TERM SURVIVAL ANALYSIS OF 36 WILMS' TUMOR PATIENTS AFTER COMBINED MODALITY THERAPY
- VernacularTitle:肾母细胞瘤综合治疗36例远期疗效
- Author:
Guoqing HU
;
Jinxiang YANG
;
Zuan ZHENG
- Publication Type:Journal Article
- Keywords:
Wilms' tumor Combined modality therapy
- From:
Chinese Journal of Radiation Oncology
1992;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
From 1965 to 1986, 36 patients with Wilms' tumor were terated by nephrectomy,postoperative irradiation and chemotherapy. The radiation doses of 1540~3920cGy were given according to an age-medulated dose scheme. All except 4 Stage I received chemotherapy. The most commonly used chemotherapeutic agent was Act-D, VCR. The overall 5-year survival rate was 61.1%(22/36) and 10-year survival rate was 56%(14/25). The 5- and 10-year survival rates were 87.5% and 80% for Stage I, 63.2% and 61.5% for stage II,33.3% and 28.6% for stage III patents. The favorable factors which led to better results were: early stages(stages I,II) and aged under 5 years . The 5-year survival rates of Stages I,II and Stage III were 70.4%(19/27) and 33.3%(3/9), respectively(P