VALIDITY OF XIAO CHAI HU TANG IN THE RADIOTHERAPY FOR SQUAMOUS CARCINOMA OF THE ESOPHAGUS-A RANDOMIZED TRIAL ON 66 CASES
- VernacularTitle:小柴胡汤合并放疗与单纯放射治疗食管鳞癌66例随机分组研究
- Author:
Xiaofeng RUAN
- Publication Type:Journal Article
- Keywords:
Xiao Chai Hu Tang Radiotherapy Esophageal carcinoma
- From:
Chinese Journal of Radiation Oncology
1992;0(01):-
- CountryChina
- Language:Chinese
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Abstract:
Xiao Chai Hu Tang (XCHT), a blended decoction of multiple chinese medicinal herbs, was tested in combination with radiation therapy for moderate or advanced squamous carcinoma of the esophagus. A total of 66 such patients were randomized into a combined group (33 patients, XCHT + radiotherapy) and a radiation only group (33 patients, RT). Telecobalt irradiation, D T 40～70 Gy, was given to the RT group. Similar telecobalt, D T 40～68 Gy with concomitant XCHT, I dose po/day to a total of 28～50 doses, was given to the combined group. The grades Ⅰ+Ⅱresponse rate of the combined group were higher than that of the RT group. The 1-, 3-and 5 year survival rates of the combined group (69.7%, 40.9%, 25.0%) also surpassed those of the RT group (45.5%, 14.3%, 9.1%). There was statistical significance in the differences in the 1-and 3-years survival rates between the combined and RT groupsFurthermore, XCHT was able to alleviate some of the toxic reactions of radiotherapy for esophageal carcinoma.
