Treatment of experimental anterior chamber fibrin formation with tissue plasminogen activator(t-PA)
- VernacularTitle:组织型纤溶酶原激活剂(t-PA)对实验性前房纤维蛋白渗出的治疗观察
- Author:
Peiquan ZHAO
- Publication Type:Journal Article
- Keywords:
Tissue plasminogen activator;
Fibrin
- From:
Ophthalmology in China
1993;0(04):-
- CountryChina
- Language:Chinese
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Abstract:
0.2ml autoplasma was injected intracamerally following paracentesis to form a quantitative and reproducible model for intraocular fibrin deposition in 14 rabbits(14 eyes).Twenty-four hours after clot formation,the rabbits were separated at random into two equal groups.One group received anterior chamber injection of t-PA(4?g),and the other group received physiological saline(PS).The tissue plasminogen activator(t-PA)treated group produced clotlysis in 5 hours,while the control group did so in 7 days.Toxicity,as measured by slit-lamp bio- microscopy,intraocular pressure,specular microscopy, and light microscopy,was not seen.
