CGRP inhibits proliferation of vascular smooth muscle cells stimulated by Endothelin
- VernacularTitle:降钙素基因相关肽抑制内皮素促血管平滑肌细胞增殖作用
- Author:
Xuedong CHI
;
Dadi NIU
;
Qing YANG
- Publication Type:Journal Article
- Keywords:
calcitonine gene related peptide (CGRP);
endothelin (ET);
vascular smooth muscle cell(VSMC)
- From:
Chinese Pharmacological Bulletin
1986;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
By means of 3H-Thymidine and3H-Leucine incorporation, we observed that CGRP inhibited the multiplication of SHR's aortic smooth muscle cells (VSMCs) and the proliferation of VSMCs stimulated by Endothelin. These results suggest that CGRP may be a natu-ral antagonist of Endothelin in human body.
