The significance of DNA-RNA double parameter quantitative analysis in the early diagnosis of laryngeal squamous cell carcinoma
- VernacularTitle:DNA-RNA双参数定量分析在早期诊断喉鳞癌中的意义
- Author:
Li LIANG
;
Weili MA
- Publication Type:Journal Article
- Keywords:
DNA/AN;
RNA/AN;
carcinoma;
squamous cell;
laryngeal neoplasms/DI
- From:Journal of Third Military Medical University
1988;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
The relative content of DNA-RNA and the nuclear area/nucleolar area ratio of the hyperplastic tissue,glottic polypus,dysplastic tissue of grade I to I laryngeal squamous cell carcinoma were measured in 33 cases with image analysis technique.It was found that the changes of DNA-RNA content and the ratio of nuclear/nucleolar area were parallel to those of the severity of the carcinoma,and RNA was markedly increased in grade 11 and I dysplastic tissue.On the basis of the current grading of laryngeal pathology,the combined determination of DNA-RNA can provide more sensitive indicators to the stages of malignant degeneration of the laryngeal squamous cell carcinoma.
