Promotion of IL-6 gene transcription by panaxatriol saponin
- VernacularTitle:人参三醇型皂甙对IL-6基因的促转录效应
- Author:
Zhigang TIAN
;
Jie LIU
;
Rui SUN
- Publication Type:Journal Article
- Keywords:
panaxatriol saponin;
human peripheral blood mononuclear cells;
interleukine-6;
RNA dot hybridization
- From:
Chinese Pharmacological Bulletin
1986;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
The RNA dot hybridization with human IL-6 cDNA showed that panaxatriol saponin (PTS) enhanced the interleukine-6(IL-6) mRNA concentration within PHA activated peripheral blood mononuclear cell (PBMC) byabout 4 folds,suggesting that PTS could promote the IL-6 gene transcription of lymphoid tissue