Mitomycin C as an adjuvant in glaucoma surgery
- VernacularTitle:用丝裂霉素C作青光眼辅助药的研究进展
- Author:
Zhijian WU
- Publication Type:Journal Article
- Keywords:
Mitomycin C/therapeutic Use;
Glaucoma/surgery
- From:
Ophthalmology in China
1993;0(03):-
- CountryChina
- Language:Chinese
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Abstract:
The most common cause of glaucoma filtration surgery failure is cicatrization secondary to fibroblast proliferation and of collagen. The high-risk factors for filtration failure include young age, aphakia, inflammation, neovascularization, and previous failure of filtration operation. Studies have shown beneficial effects of a single dose intraoperative mitomycin C,an antimetabolite, in inhibiting fibroblast proliferation and slceral wound cicatrization, thereby promoting success in eyes of poor surgical prognosis. Corneal complications have been minor.
