A study on the mechanism of insulin resistance of adipose tissue after scalding in rats
- VernacularTitle:严重烫伤大鼠脂肪组织胰岛素抵抗机制的研究
- Author:
Linshui XU
;
Xigui WU
- Publication Type:Journal Article
- Keywords:
burns;
insulin resistance;
receptors;
insulin;
phosphodiesterases
- From:Journal of Third Military Medical University
1983;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
The possible mechanism of insulin resistance of the adipose tissue after burn injury was studied.The binding activity of the insulin receptors,the insulin effects on insulin-sensitive phosphodiesterase(PDE)and the level of free fatty acid(FFA)and cAMP were observed for 4 d in the adipose tissue of the rats inflicted with 30% TBSA full thickness scalding. It was found that the maximal binding capacity of the insulin receptors was greatly decreased(P
