A study on the relationship between prognosis and debride-ment time in rats with phosphorus burns
- VernacularTitle:磷烧伤预后与清创时间关系的实验研究
- Author:
Shufang XIA
;
Mingjing WEI
;
Zongcheng YANG
- Publication Type:Journal Article
- Keywords:
burns;
chemical/phosphorus;
debridement;
prognosis
- From:Journal of Third Military Medical University
1983;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Male Wistar rats were randomized into 3 groups:The rats of group I received sham burning to serve as the control and those of groups and Ⅲ were inflicted with 20% and 30% TBSA third degree phosphorus burns respectively.No treatment was given to group Ⅱ.Group Ⅲwas further divided into 2:The rats of subgroup Ⅰ were debrided immediately and those of subgroup Ⅱ in the 6th hour postburn.The findings were as follows;(l)The tissue content of phosphorus was more significantly decreased in subgroup Ⅰ than in subgroup Ⅱ-(2)Twenty-eight rats of subgroup Ⅰ all survived while 9 of the 44 rats of subgroup Ⅱ died with a mortality rate of 20.5%.The mortality rate of group Ⅱ was 37.5%(3/8).(3)The recovery of serum electrolytes and other biochemical parameters occurred earlier in subgroup I.Our findings suggest that debridement as early as possible after phosphorus burns contributes significantly to the decrease of the victims mortality.