HEPATITIS C VIRUS AND HEPATITIS B VIRUS INFECTION IN PATIENTS WITH PRI-MARY HEPATIC CARCINOMA NEGATIVE FOR HBV IMMUNOLOGICAL MARKERS
- VernacularTitle:HBV免疫标志阴性肝癌病人中HCV和HBV感染
- Author:
Jianmin YANG
;
Weiwen LIU
;
Huayuan JIN
- Publication Type:Journal Article
- Keywords:
Hepatitis C virus;
Hepatitis B virus;
Polymersae chain reaction;
Hepatoma
- From:
Medical Journal of Chinese People's Liberation Army
1981;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Serum hepatitis C virus (HCV) RNA and HBV DNA were assayed in 38 patients with primary hepatic carcinoma (PHC) negative for all serum HBV immunological markers (HBsAg, HBsAb, HBeAg, HBeAb and HBcAb) by polymerase chain reaction (PCR). It was found that either HCV RNA or HBV DNA or both were detectable in 28 cases (73.7%) among the 38 patients. Of these patients, single HCV RNA- positive, single HBV DNA-positive and both HCV RNA and HBV DNA-positive were observed in 7(18.4%), 12(31.6%) and 9(23.7%) cases, respectively. The results suggest that (1) HCV infection may also play an important role in the development of PHC in Chongqing; and (2) about half of the PHC patients negative for all the serum HBV immunological markers are still associated with HBV infection.
