PEDIGREE ANALYSIS OF OTOSCLEROSTIC FAMILIES
- VernacularTitle:耳硬化症的家族调查与分析
- Author:
Suzhen ZHANG
;
Sichang JIANG
;
Weiyan YANG
;
Yaoyun FANG
- Publication Type:Journal Article
- Keywords:
Otosclerosis;
Hearing loss;
Genetic;
Propositi;
Footplat lesion
- From:
Medical Journal of Chinese People's Liberation Army
1981;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
This paper presented the hereditary pattern of otosclerosis in families. Among 1500 cases there were 13 patients, belonging to 6 families, and 20 ears were surgically treated. There was often a marked similarity in clinical features of affected siblings within the same family.The clinical characteristics are as following: (1) The age at inset of hearing loss seems similar. There is a difference of 1 or 2 years in two families znc 3 to 10 years in the other four. (2) The side of first hearing loss is the same in affected individuals of 6 families. (3) The propositi are females in 5 families (83.3%). (4) Auditory curve of hearing loss is similar in 4 familiers, and different in the other two. (5) The footplate lesions are similar in macroscopic features, thin footplate in two fimalies and thick footplate in the other four.
