The function-restorative effects of implanted embryonic spinal cord on acutely injured cord of adult rats
- VernacularTitle:大鼠胚胎脊髓植入对成年鼠急性脊髓损伤的功能修复作用
- Author:
Bingcang LI
;
Yingyu LI
;
Yamin WU
- Publication Type:Journal Article
- Keywords:
spinal cord injuries;
spinal cord/TR;
embryonic spinal cord
- From:Journal of Third Military Medical University
1983;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Spinal sensory evoked potential(SSEP)and spinal motor evoked potential(SMEP)of the injured spinal cord of the host rats were determined on the 7th,15th,30th.60th,120th and 240th day after they received implantation of the embryonic spinal cord from the fetus of E14 rats.The motor function of the hind limbs of the host rats were also observed.The rats with simple cord injury and those with cord injury and implantation of a piece of skeletal muscle served as the controls.It was found that the locomotor function of the host rats could be recovered on the 30th day after implantation,but the latent period of both SSEP and SMEP became normal on the 240th day.At that time,the latent period of evoked potentials of the 2 control groups also recovered gradually.It is believed that embryonic spinal cord may have effects on the recovery of the locomotor function of the host rats but more sophisticated methods are imperative to clarify the interela-tionship between the host tissue and the graft.
