Effect of polysaccharide sulphate on reducing blood glucose
- VernacularTitle:藻酸双酸钠的降血糖作用
- Author:
Xuezeng ZHAO
;
Xinming WANG
;
Ye XIA
;
Qiuyian ZHANG
- Publication Type:Journal Article
- Keywords:
polysaccharide sulphate;
Tolbutamide;
adrenaline;
glucose tolerance;
blood glucose
- From:
Chinese Pharmacological Bulletin
1987;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Polysaccharide sulphate (PSS) 1. 8, 5. 4 and 18mg ? kg-1 ig could remarkably reduce blood glucose of alloxan - induced diabetes in rabbits . The doses of PSS could decrease the high blood glucose caused by adrenaline . PSS 1. 8 and 5. 4mg ? kg-1 could not reduce blood glucose concentration in normal rabbits, but PSS 18mg ? kg-1 could do. The glucose to lerance test showed that PSS 5. 4 and 18mg ?kg-1 could reduce the increase of blood glucose level caused by glucose loading after administration of glucose in rats (5g ? kg-1, ig) and could also persistently decrease blood glucose of alloxan - induced diabetes in rats after the doses of PSS ig for 5d.
