The relationship between hepatitis C virus infection and primary hepatic carcinoma: An investigation on serum HCV RNA in different populations
- VernacularTitle:丙型肝炎病毒感染与原发性肝癌的关系——不同人群血清HCV RNA的调查
- Author:
Jianmin YANG
;
Weiwen LIU
;
Huayuan JIN
- Publication Type:Journal Article
- Keywords:
hepatitis, viral, human;
hepatitis B virus;
hepatoma;
polymerase chain reaction
- From:Journal of Third Military Medical University
1984;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
A preliminary investigation on the serum HCV RNA in 182 patients with different chronic liver diseases and 35 blood donors was performed with "nested" polymerase chair reaction.The findings were as follows;(1)Serum HCV RNA was detected in 36.6%(34/93)cases of primary hepatic carcinoma(PHC),31.7%(20/63)cases of liver cirrhosis(LC),15.4%(4/ 26)cases of chronic hepatitis(CH)and 2.9%(1/35)blood donors.(2)Most of the HCV RNA positive cases were accompanied with positive serum HBsAg/HBV DNA.15.1%(14/93)of PHC,3.2%(2/63)of LC and 3.8%(1/26)of CH was positive only for HCV RNA.The findings suggest that about 20% of PHC are related to the coinfection of HCV and HBV,while 15% of PHC are related to HCV infection only.
