EFFECT OF Se-SUPPLEMENTATION ON MONOAMINE OXIDASE ACTIVITY IN MYOCARDIAL MITOCHONDRIA OF RATS FED ON GRAINS FROM KESHAN DISEASE AREA
- VernacularTitle:补硒对克山病病区粮饲养大鼠心肌线粒体单胺氧化酶活性的影响
- Author:
Lanhua ZHOU
;
Gaofeng FAN
;
Guanglu XU
;
Shichen WANG
;
Shichen WANG
;
Kai ZHANG
- Publication Type:Journal Article
- Keywords:
selenium keshan disease area grains monoamine oxidase;
myocardial mitochondria
- From:
Acta Nutrimenta Sinica
1956;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Three groups of Sprague-Dawley rats were fed on low-Se diet frow Keshan disease area, Se-supplemented diet and stock diet respectively, for observing the effect of Se on mitochoadrial monoamine oxidase (MAO) activities in myocardia. The results showed that cardiac mitochondrial MAO activities in the Se-deficient group were significantly decreased as compared to both the Se-supplemented and stock diet group, and Se content in plasma and GSH-Px activity in. red blood cells also were significantly reduced at 30, 60 and 90 days of feeding. In Se-supplemented group MAO and GSH-Px activities as well as Se content were comparable to levels in the stock diet group.
