Comparative Study on Tryptic Peptide Mapping of Globin Beta Chains and the Genotype from Nineteen Inbred Strains of Mice
- VernacularTitle:19个近交品系小鼠珠蛋白?肽谱的建立及遗传型的比较
- Author:
Shukui SONG
;
Kaiyuan HU
;
Jianxin LI
- Publication Type:Journal Article
- Keywords:
globin;
genotype;
peptides;
mice
- From:
Academic Journal of Second Military Medical University
1982;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
This study represents the first description of structural variations in the globin beta chains of 19 strains of inbred mice. The trypic pep tide mapping of beta chains of globin from BALB/c, BALB/cA, BALB/cJ, BALBcJ-nu, BALB/nu/ + ,BALB/cyJax,B10,B10A/sui,C57BL/6,C57BL/10snJ,SMMC/B,SMMC/C, C3H/He, CFW, DBA/2,SWI,Swars/nu/+,SSB and 129/sv strains of mice was established. The results showed that the position of peptide spots upon fingerprint mapping of beta chains was obviously different in comparison with each other. The different patterns of variability and polymorphism found in the various mouse species may then have come into being as a consequence of the action of selective forces on the various new beta chains which were created by some exchange processes.