Changes of acid phosphatase and cytochrome oxidase in hepatic acini during acute obstructive cholangitis in rats
- VernacularTitle:急性胆道感染时肝腺泡酸性磷酸酶与细胞色素氧化酶活性的变化
- Author:
Jianping GONG
;
Benli HAN
;
Ding LUO
- Publication Type:Journal Article
- Keywords:
hepatic acinus;
cholangitis;
acid phosphatase;
cytochrome oxidase;
actue disease
- From:Journal of Third Military Medical University
1984;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
The changes of acid phosphatase(ACP)and cytochrome oxidase(CO)in the hepatic acini were investigated with image analysis in 90 Wistar rats after acute obstructive cholangitis was inflicted.It was found that the activity of ACP was significantly increased in the 2nd hour after surgery and markedly decreased in the 12th hour and these changes were predominantly located in acinur zone 1 of the hepatocytes.The activity of CO was decreased progressively after surgery,and these changes were quite marked in the acinur zone 3 of the hepatocytes.These findings indicate that the reactions towards acute obstructive cholangitis are different in the different acinur zones of the hepatocytes.
